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CAMBRIDGE, Mass., 26. Mai 2026--(BUSINESS WIRE)--Scholar Rock (NASDAQ: SRRK), ein globaler Biopharmazeutikum-Unternehmen, das sich auf die Verbesserung des Lebens von Kindern und Erwachsenen mit spinaler Muskelatrophie (SMA) und weiteren seltenen, schweren und hemmenden neuromuskulären Krankheiten konzentriert, indem es seine führende Plattform in der Myostatin-Biologie anwendet, um die Muskuloskelettale Gesundheit zu fördern. Das Unternehmen gab heute bekannt, dass das Management auf der Goldman Sachs 47. jährlichen Global Healthcare Konferenz in Miami, FL am Dienstag, den 9. Juni 2026 um 10:00 Uhr ET präsentieren wird.

Haftungsausschluss: Der Text wurde mit Hilfe einer KI zusammengefasst und übersetzt. Für Aussagen aus dem Originaltext wird keine Haftung übernommen!

Zusammenfassung (ca. 500 Wörter)

Die Aktien von Scholar Rock Holding Corporation (SRRK) stiegen am Dienstag um 14 % an, nachdem das Unternehmen die Einreichung bei der FDA zur Genehmigung seiner investigativen, muskelzielgerichteten Therapie, apitegromab, zur Behandlung von Spinalmuskeldystrophie (SMA) bei Kindern und Erwachsenen erneut eingereicht hat. Diese erneuten Einreichung zielt darauf ab, frühere Bedenken der FDA auszuräumen.

Das Unternehmen erwartet, dass die FDA die überarbeitete Einreichung innerhalb von 30 Tagen akzeptiert, was zu einer Überprüfung führt, die potenziell bis zu sechs Monate dauern kann. Wenn genehmigt, wird eine endgültige Entscheidung für September 2026 prognostiziert. Diese positive Entwicklung folgt auf eine erste Einreichung letzten Jahres, die eine Prioritätsprüfung erhielt, aber letztendlich zu einem “Complete Response Letter” (CRL) wegen Problemen in der Einrichtung der Catalent zur Endverpackung von Novo Nordisk in Indiana führte. Entscheidend ist, dass das CRL keine Probleme mit der Wirksamkeit oder Sicherheit von apitegromab aufzeigte.

Scholar Rock hat aktiv mit der FDA und Catalent zusammengearbeitet, um die Mängel zu beheben, indem es ein zweites, in den USA ansässiges Endverpackungszentrum in die erneuten Einreichungen einbezog. Diese Ergänzung soll die Zuverlässigkeit der Lieferkette stärken und die erwartete kommerzielle Nachfrage unterstützen.

Der Genehmigungspfad basiert auf Daten aus einer entscheidenden, späten Phase klinischen Studien, die zeigte, dass apitegromab die motorische Funktion bei SMA-Patienten signifikant und klinisch relevant verbesserte. Eine ähnliche Einreichung wird derzeit in der Europäischen Union geprüft, mit einer Entscheidung, die voraussichtlich Mitte 2026 fallen wird.

Wenn apitegromab genehmigt wird, wird es in einem hochwettbewerbsfähigen Markt konkurrieren, der von etablierten Unternehmen wie Biogens Spinraza (ein injizierbares Medikament), Novartis’ Zolgensma (eine Gentherapie) und Rohes Evrysdi (ein orales Medikament) dominiert. Diese Behandlungen haben erhebliche Umsätze generiert und stellen eine erhebliche kommerzielle Chance dar.

Derzeit hat Scholar Rock keine zugelassenen Produkte. Die Erlangung der FDA-Zulassung für apitegromab wäre ein Wendepunkt, der das Unternehmen von einem klinisch-entwicklungsfähigen Biotehnologieunternehmen zu einem kommerziell erfolgreichen Unternehmen machen würde, das einen wiederkehrenden Umsatz generiert. Die Aktienperformance spiegelt den Optimismus der Anleger in Bezug auf diese potenzielle Verschiebung wider.

Apitegromab wirkt, indem es Myostatin, ein Protein, das an Muskelwachstum beteiligt ist, hemmt, bietet einen gezielten Ansatz zur Behandlung von neuromuskulären Erkrankungen. Neben SMA prüft Scholar Rock auch apitegromab für facioscapulohumeral muskuläre Dystrophie (FSHD) und plant, im Laufe dieses Jahres eine Mid-Stage-Studie einzuleiten.

SRRKs aktueller Zacks-Rang von #3 (Hold) spiegelt die vorsichtige Optimierung in Bezug auf die erneuten Einreichungen wider, während die Aktie im Vergleich zur breiteren Biotechnologiebranche bis zum Jahreszeitende überlegen geliefert hat.

Haftungsausschluss: Der Text wurde mit Hilfe einer KI zusammengefasst und übersetzt. Für Aussagen aus dem Originaltext wird keine Haftung übernommen!

The S&P 500 Index ($SPX) (SPY) on Tuesday closed up +2.91%, the Dow Jones Industrial Average ($DOWI) (DIA) closed up +2.49%, and the Nasdaq 100 Index ($IUXX) (QQQ) closed up +3.43%.  June E-mini S&P futures (ESM26) rose +2.88%, and June E-mini Nasdaq futures (NQM26) rose +3.42%.

Stock indexes rallied sharply on Tuesday in hopes that an end to the Iran war is near.  The Wall Street Journal reported Tuesday that President Trump signaled he was willing to end the US military campaign against Iran even if the Strait of Hormuz remains closed.  The report said Mr. Trump believes the US should wind down hostilities while pressuring Iran diplomatically to reopen the Strait.  If that fails, the US will press allies in Europe and the Gulf to take the lead on reopening the waterway.  US and Israeli forces pressed ahead with attacks on Iran on Tuesday, while Iran hit a Kuwaiti oil tanker off Dubai in a drone attack, and the UAE reported a drone attack. Join 200K+ Subscribers: Find out why the midday Barchart Brief newsletter is a must-read for thousands daily.

Stocks added to their gains, and crude oil prices tumbled Tuesday afternoon after Iran signaled openness to resolving the war.  Iranian President Masoud Pezeskhian said his country had the "necessary will to end this war," provided that hostilities end on all fronts and that Iran's sovereignty over the Strait of Hormuz is recognized.

Falling bond yields are also supportive of stocks, as the 10-year T-note yield dropped to a 1-week low of 4.28% on Tuesday.  Bond yields declined amid hopes that an end to the Iran war will lower energy prices, easing inflation concerns.  Stocks also found support on Tuesday after the US Mar consumer confidence index unexpectedly rose.

The US Jan S&P CaseShiller composite-20 home price index rose +1.18% y/y, weaker than expectations of +1.38% y/y and the smallest pace of increase in 2.5 years.

The US Mar MNI Chicago PMI fell -4.9 to 52.8, weaker than expectations of 55.0.

The Conference Board US Mar consumer confidence index unexpectedly rose +0.8 to 91.8, stronger than expectations of a decline to 87.9.

US Feb JOLTS job openings fell -358,000 to 6.882 million, weaker than expectations of 6.890 million.

Hawkish comments on Tuesday from Kansas City Fed President Jeff Schmid were negative for stocks, as he said he's "more focused on the risks to inflation at this time" and that he's concerned inflation will get stuck closer to 3% as the recent surge in energy prices will likely feed through to core inflation.

Signs of strength in China’s economy are supportive for global growth prospects and stocks.  The China March manufacturing PMI rose +1.4 to 50.4, better than expectations of 50.1 and the strongest pace of expansion in a year.  Also, the China March non-manufacturing PMI rose by +0.6 to 50.1, better than expectations of 49.9.

Crude oil prices (CLK26) fell from a 3-week high on Tuesday but remain supported despite President Trump signaling he is willing to end the war with Iran, as the Strait of Hormuz remains effectively closed.  The closure of the Strait of Hormuz, through which about a fifth of the world’s oil and natural gas flows, has choked off oil and gas flows due to Iran’s attacks on shipping in the waterway and forced Gulf producers to cut output because they can’t export from the region.  Iran is also seeking to control ship transit through the Strait of Hormuz, asking vessels to provide lists of crew and cargo, along with voyage details and bills of lading if they want to travel through the waterway.  Goldman Sachs warns that crude prices could exceed the 2008 record high of close to $150 a barrel if flows through the Strait of Hormuz remain depressed through March.

The International Energy Agency said last Monday that more than 40 energy sites across nine countries in the Middle East have been "severely or very severely" damaged, potentially prolonging disruptions to global supply chains once the war in Iran ends.

The markets are discounting a 3% chance for a +25 bp FOMC rate hike at the April 28-29 policy meeting.

Overseas stock markets settled mixed on Tuesday.  The Euro Stoxx 50 closed up +0.50%.  China's Shanghai Composite fell from a 1-week high and closed down -0.80%.  Japan's Nikkei Stock 225 fell to a 3-month low and closed down -1.58%.

Interest Rates

June 10-year T-notes (ZNM6) on Tuesday closed up by +7.5 ticks.  The 10-year T-note yield fell -4.1 bp to 4.307%.  June T-notes rose to a 1-week high on Tuesday, and the 10-year T-note yield fell to a 1-week low of 4.283%.  T-notes moved higher on Tuesday in hopes that an end to the Iran war will lower energy prices and ease inflation concerns.  T-notes fell from their best level after the US Mar consumer confidence index unexpectedly rose and after Kansas City Fed President Jeff Schmid said he's "more focused on the risks to inflation at this time."

European government bond yields moved lower on Tuesday.  The 10-year German bund yield fell -3.1 bp to 3.004%.  The 10-year UK gilt yield fell -1.9 bp to 4.916%.

Eurozone Mar CPI rose +2.5% y/y, the most in 14 months, but below expectations of +2.6% y/y.  Mar core CPI rose +2.3% y/y, weaker than expectations of +2.4% y/y.

German Feb retail sales unexpectedly fell -0.6% m/m, weaker than expectations of a +0.3% m/m increase.

ECB Governing Council member Madis Muller said, "The ECB can't rule out changes in interest rates already in April if energy prices remain at a high level for a long time."

Swaps are discounting a 55% chance of a +25 bp ECB rate hike at its next policy meeting on April 30.

US Stock Movers

The Magnificent Seven technology stocks are climbing today, helping lift the overall market.  Meta Platforms (META) closed up more than +6%, and Nvidia (NVDA) and Alphabet (GOOGL) closed up more than +5%.  Also, Tesla (TSLA) closed up more than +4%, and Amazon.com (AMZN) and Microsoft (MSFT) closed up more than +3%.  In addition, Apple (AAPL) closed up more than +2%.

Marvell Technology (MRVL) closed up more than +12% to lead gainers in the Nasdaq 100 and chip stocks after Nvidia said it is investing $2 billion in the company.  Also, ON Semiconductor (ON) closed up more than +11% to lead gainers in the S&P 500, and Sandisk (SNDK) and ARM Holdings Plc (ARM) closed up more than +10%.  In addition, Western Digital (WDC), Intel (INTC), Seagate Technology Holdings Plc (STX), and Microchip Technology (MCHP) closed up more than +7%, and KLA Corp (KLAC) and Lam Research (LRCX) closed up more than +6%.  Finally, Applied Materials (AMAT), Broadcom (AVGO), and ASML Holding NV (ASML) closed up more than +5%, and Micron Technology (MU), Analog Devices (ADI), and NXP Semiconductors NV (NXPI) closed up more than +4%.

Airline stocks surged on Tuesday as crude oil prices fell by more than -1% in hopes that an end to the Iran war is near.  United Airlines Holdings (UAL) closed up more than +8%, and Alaska Air Group (ALK) closed up more than +7%.  Also, American Airlines Group (AAL) and Delta Air Lines (DAL) closed up more than +5%, and Southwest Airlines (LUV) closed up more than +3%.

Home builders and building suppliers moved higher on Tuesday after the 10-year T-note yield fell to a 1-week low, which lowers mortgage rates and supports housing demand. Builders Firstsource (BLDR) and Toll Brothers (TOL) closed up more than +4%, and DR Horton (DHI) and Pulte Group (PHM) closed up more than +3%.  Also, Lennar (LEN) and KB Home (KBH) closed up more than +2%.

Energy producers and energy service providers moved lower on Tuesday after WTI crude oil fell from a 3-week high, dropping by more than 1%.  APA Corp (APA) and Devon Energy (DVN) closed down more than -2%, and Chevron (CVX) closed down more than -1% to lead losers in the Dow Jones Industrials. Also, Occidental Petroleum (OXY), Exxon Mobil (XOM), Phillips 66 (PSX), and Valero Energy (VLO) closed down more than -1%.

Apellis Pharmaceuticals (APLS) closed up more than +135% after being acquired by Biogen for $5.6 billion, or about $41 a share.  Biogen (BIIB) closed down more than -2% on the news.

Centessa Pharmaceuticals (CNTA) closed up more than +44% after Eli Lilly agreed to buy the company for about $7.8 billion or $38 a share, plus a further $9 a share if three milestone targets are met.

Scholar Rock (SRRK) closed up by more than +14% after it resubmitted its Biologics License Application for apitegromab, a muscle-targeted therapy for spinal muscular atrophy.

Nebius Group NV (NBIS) closed up more than +12% after saying it plans to build a 310-megawatt server facility in Finland.

Caterpillar (CAT) closed up more than +6% to lead gainers in the Dow Jones Industrials after Barclays raised its price target on the stock to $700 from $625.

FactSet Research Systems (FDS) closed up more than +6% after reporting Q2 revenue of $611 million, better than the consensus of $604.9 million, and raising its full-year revenue forecast to $2.45 billion to $2.47 billion from a previous estimate of $2.42 billion to $2.45 billion, above the consensus of $2.45 billion.

Phreesia (PHR) is down more than -26% after cutting its 2027 revenue forecast to $510 million to $520 million from a previous forecast of $545 million to $559 million, well below the consensus of $550.9 million.

Constellation Energy (CEG) closed down more than -6% to lead losers in the S&P 500 and Nasdaq 100 after forecasting 2026 adjusted operating EPS of $11 to $12.00, the midpoint below the consensus of $11.72.

McCormick & Co (MKC) closed down more than -6% after agreeing to acquire Unilever’s Food business for $15.7 billion in cash and $29.7 billion of stock.

Earnings Reports(4/1/2026)

Conagra Brands Inc (CAG), Lamb Weston Holdings Inc (LW), MSC Industrial Direct Co Inc (MSM). On the date of publication, Rich Asplund did not have (either directly or indirectly) positions in any of the securities mentioned in this article. All information and data in this article is solely for informational purposes. For more information please view the Barchart Disclosure Policy here.

More news from Barchart

Stock Index Futures Rally on Prospect of End to Middle East Conflict, U.S. Economic Data and Fed Speak in FocusStocks Set to Open Higher as Bond Yields Fall on Fading Rate-Hike Bets, U.S. Jobs Data and Powell’s Remarks AwaitedIran, Oil Prices and Other Key Things to Watch this WeekMeta Platforms Just Cut Jobs. Does That Make META Stock a Buy, Sell, or Hold Before Q2 Starts?

The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

Haftungsausschluss: Der Text wurde mit Hilfe einer KI zusammengefasst und übersetzt. Für Aussagen aus dem Originaltext wird keine Haftung übernommen!

The S&P 500 Index ($SPX) (SPY) today is up +1.02%, the Dow Jones Industrial Average ($DOWI) (DIA) is up +0.67%, and the Nasdaq 100 Index ($IUXX) (QQQ) is up +1.10%.  June E-mini S&P futures (ESM26) are up +1.10%, and June E-mini Nasdaq futures (NQM26) are up +1.15%.

Stock indexes are moving sharply higher today after the Wall Street Journal reported that President Trump had signaled he was willing to end the US military campaign against Iran even if the Strait of Hormuz remains closed.  The report said Mr. Trump believes the US should wind down hostilities while pressuring Iran diplomatically to reopen the Strait.  If that fails, the US will press allies in Europe and the Gulf to take the lead on reopening the waterway.  US and Israeli forces pressed ahead with attacks on Iran today, while Iran hit a Kuwaiti oil tanker off Dubai in a drone attack, and the UAE reported a drone attack. Join 200K+ Subscribers: Find out why the midday Barchart Brief newsletter is a must-read for thousands daily.

Falling bond yields are also supportive of stocks, as the 10-year T-note yield dropped to a 1-week low of 4.30% today.  Bond yields are declining amid hopes that an end to the Iran war will lower energy prices, easing inflation concerns.  Stocks also found support today after the US Mar consumer confidence index unexpectedly rose.  Stock indexes fell back from their best levels as crude prices rose more than +1% to a 3-week high.

The US Jan S&P CaseShiller composite-20 home price index rose +1.18% y/y, weaker than expectations of +1.38% y/y and the smallest pace of increase in 2.5 years.

The US Mar MNI Chicago PMI fell -4.9 to 52.8, weaker than expectations of 55.0.

The Conference Board US Mar consumer confidence index unexpectedly rose +0.8 to 91.8, stronger than expectations of a decline to 87.9.

US Feb JOLTS job openings fell -358,000 to 6.882 million, weaker than expectations of 6.890 million.

Signs of strength in China’s economy are supportive for global growth prospects and stocks.  The China March manufacturing PMI rose +1.4 to 50.4, better than expectations of 50.1 and the strongest pace of expansion in a year.  Also, the China March non-manufacturing PMI rose by +0.6 to 50.1, better than expectations of 49.9.

Crude oil prices (CLK26) rose to a 3-week high today and remain supported despite President Trump signaling he is willing to end the war with Iran, as the Strait of Hormuz remains effectively closed.  The closure of the Strait of Hormuz, through which about a fifth of the world’s oil and natural gas flows, has choked off oil and gas flows due to Iran’s attacks on shipping in the waterway and forced Gulf producers to cut output because they can’t export from the region.  Iran is also seeking to control ship transit through the Strait of Hormuz, asking vessels to provide lists of crew and cargo, along with voyage details and bills of lading if they want to travel through the waterway.  Goldman Sachs warns that crude prices could exceed the 2008 record high of close to $150 a barrel if flows through the Strait of Hormuz remain depressed through March.

The International Energy Agency said last Monday that more than 40 energy sites across nine countries in the Middle East have been "severely or very severely" damaged, potentially prolonging disruptions to global supply chains once the war in Iran ends.

The markets are discounting a 3% chance for a +25 bp FOMC rate hike at the April 28-29 policy meeting.

Overseas stock markets are mixed today.  The Euro Stoxx 50 is up +0.83%.  China's Shanghai Composite fell from a 1-week high and closed down -0.80%.  Japan's Nikkei Stock 225 fell to a 3-month low and closed down -1.58%.

Interest Rates

June 10-year T-notes (ZNM6) today are up by +8 ticks.  The 10-year T-note yield is down -2.8 bp to 4.321%.  June T-notes rose to a 1-week high today, and the 10-year T-note yield fell to a 1-week low of 4.295%.  T-notes are climbing today on hopes that an end to the Iran war will lower energy prices and ease inflation concerns.  T-notes fell from their best level after the US Mar consumer confidence index unexpectedly rose.

European government bond yields are moving lower today.  The 10-year German bund yield is down -0.6 bp to 3.029%.  The 10-year UK gilt yield is down -2.0 bp to 4.914%.

Eurozone Mar CPI rose +2.5% y/y, the most in 14 months, but below expectations of +2.6% y/y.  Mar core CPI rose +2.3% y/y, weaker than expectations of +2.4% y/y.

German Feb retail sales unexpectedly fell -0.6% m/m, weaker than expectations of a +0.3% m/m increase.

ECB Governing Council member Madis Muller said, "The ECB can't rule out changes in interest rates already in April if energy prices remain at a high level for a long time."

Swaps are discounting a 50% chance of a +25 bp ECB rate hike at its next policy meeting on April 30.

US Stock Movers

The Magnificent Seven technology stocks are climbing today, helping lift the overall market.  Nvidia (NVDA) and Meta Platforms (META) are up more than +3%, and Amazon.com (AMZN), Tesla (TSLA), and Alphabet (GOOGL) are up more than +2%.  In addition, Microsoft (MSFT) is up more than +1%, and Apple (AAPL) is up +0.48%.

Marvell Technology (MRVL) is up more than +8% to lead gainers in the Nasdaq 100, and chip stocks are higher after Nvidia said it is investing $2 billion in the company.  Also, ARM Holdings Plc (ARM) is up more than +6%, and Western Digital (WDC), ON Semiconductor (ON), and Sandisk (SNDK) are up more than +5%.  In addition, Seagate Technology Holdings Plc (STX) is up more than +4%, and Lam Research (LRCX), Broadcom (AVGO), Intel (INTC), and Microchip Technology (MCHP) are up more than +3%.  Finally, NXP Semiconductors NV (NXPI), KLA Corp (KLAC), Applied Materials (AMAT), and ASML Holding NV (ASML) are up more than +2%.

Home builders and building suppliers are moving higher today after the 10-year T-note yield fell to a 1-week low, which lowers mortgage rates and supports housing demand. Builders Firstsource (BLDR) and Toll Brothers (TOL) are up more than +2%.  Also, Lennar (LEN) and Pulte Group (PHM) are up more than +1%, and KB Home (KBH) is up more +0.42%, and DR Horton (DHI) is up +0.40%.

Apellis Pharmaceuticals (APLS) is up more than +136% after being acquired by Biogen for $5.6 billion, or about $41 a share.  Biogen (BIIB) is down more than -4% on the news.

Centessa Pharmaceuticals (CNTA) is up more than +44% after Eli Lilly agreed to buy the company for about $7.8 billion or $38 a share, plus a further $9 a share if three milestone targets are met.

Scholar Rock (SRRK) is up by more than +12% after it resubmitted its Biologics License Application for apitegromab, a muscle-targeted therapy for spinal muscular atrophy.

FactSet Research Systems (FDS) is up more than +7% to lead gainers in the S&P 500 after reporting Q2 revenue of $611 million, better than the consensus of $604.9 million, and raising its full-year revenue forecast to $2.45 billion to $2.47 billion from a previous estimate of $2.42 billion to $2.45 billion, above the consensus of $2.45 billion.

Nebius Group NV (NBIS) is up more than +5% after saying it plans to build a 310-megawatt server facility in Finland.

Phreesia (PHR) is down more than -26% after cutting its 2027 revenue forecast to $510 million to $520 million from a previous forecast of $545 million to $559 million, well below the consensus of $550.9 million.

Constellation Energy (CEG) is down more than -8% to lead losers in the S&P 500 and Nasdaq 100 after forecasting 2026 adjusted operating EPS of $11 to $12.00, the midpoint below the consensus of $11.72.

McCormick & Co (MKC) is down more than -6% after agreeing to acquire Unilever’s Food business for $15.7 billion in cash and $29.7 billion of stock.

Colgate-Palmolive (CL) is down more than -2% after TD Cowen downgraded the stock to hold from buy.

Earnings Reports(3/31/2026)

FactSet Research Systems Inc (FDS), McCormick & Co Inc/MD (MKC), nCino Inc (NCNO), NIKE Inc (NKE), PVH Corp (PVH), RH (RH), TD SYNNEX Corp (SNX). On the date of publication, Rich Asplund did not have (either directly or indirectly) positions in any of the securities mentioned in this article. All information and data in this article is solely for informational purposes. For more information please view the Barchart Disclosure Policy here.

More news from Barchart

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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

Haftungsausschluss: Der Text wurde mit Hilfe einer KI zusammengefasst und übersetzt. Für Aussagen aus dem Originaltext wird keine Haftung übernommen!

The S&P 500 Index ($SPX) (SPY) today is up +1.33%, the Dow Jones Industrial Average ($DOWI) (DIA) is up +1.10%, and the Nasdaq 100 Index ($IUXX) (QQQ) is up +1.45%.  June E-mini S&P futures (ESM26) are up +1.48%, and June E-mini Nasdaq futures (NQM26) are up +1.59%.

Stock indexes are moving sharply higher today after the Wall Street Journal reported that President Trump had signaled he was willing to end the US military campaign against Iran even if the Strait of Hormuz remains closed.  The report said Mr. Trump believes the US should wind down hostilities while pressuring Iran diplomatically to reopen the Strait.  If that fails, the US will press allies in Europe and the Gulf to take the lead on reopening the waterway.  US and Israeli forces pressed ahead with attacks on Iran today, while Iran hit a Kuwaiti oil tanker off Dubai in a drone attack, and the UAE reported a drone attack. Join 200K+ Subscribers: Find out why the midday Barchart Brief newsletter is a must-read for thousands daily.

Falling bond yields are also supportive of stocks, as the 10-year T-note yield dropped to a 1-week low of 4.30% today.  Bond yields are declining after WTI crude oil prices fell from a 3-week high today and are little changed, easing inflation concerns.

Signs of strength in China’s economy are supportive for global growth prospects and stocks.  The China March manufacturing PMI rose +1.4 to 50.4, better than expectations of 50.1 and the strongest pace of expansion in a year.  Also, the China March non-manufacturing PMI rose +0.6 to 50.1, better than expectations of 49.9.

Crude oil prices (CLK26) remain supported despite President Trump signaling he is willing to end the war with Iran, as the Strait of Hormuz remains effectively closed.  The closure of the Strait of Hormuz, through which about a fifth of the world’s oil and natural gas flows, has choked off oil and gas flows due to Iran’s attacks on shipping in the waterway and forced Gulf producers to cut output because they can’t export from the region.  Iran is also seeking to control ship transit through the Strait of Hormuz, asking vessels to provide lists of crew and cargo, along with voyage details and bills of lading if they want to travel through the waterway. Goldman Sachs warns that crude prices could exceed the 2008 record high of close to $150 a barrel if flows through the Strait of Hormuz remain depressed through March.

The International Energy Agency said last Monday that more than 40 energy sites across nine countries in the Middle East have been "severely or very severely" damaged, potentially prolonging disruptions to global supply chains once the war in Iran ends.

The markets are discounting a 3% chance for a +25 bp FOMC rate hike at the April 28-29 policy meeting.

Overseas stock markets are mixed today.  The Euro Stoxx 50 is up +0.60%.  China's Shanghai Composite fell from a 1-week high and closed down -0.80%.  Japan's Nikkei Stock 225 fell to a 3-month low and closed down -1.58%.

Interest Rates

June 10-year T-notes (ZNM6) today are up by +10 ticks.  The 10-year T-note yield is down -4.6 bp to 4.303%.  June T-notes rose to a 1-week high today, and the 10-year T-note yield fell to a 1-week low of 4.295%.  T-notes are climbing today after WTI crude oil prices fell from a 3-week high and were little changed, easing inflation concerns.

European government bond yields are moving lower today.  The 10-year German bund yield is down -2.1 bp to 3.014%.  The 10-year UK gilt yield is down -3.9 bp to 4.895%.

Eurozone Mar CPI rose +2.5% y/y, the most in 14 months, but below expectations of +2.6% y/y.  Mar core CPI rose +2.3% y/y, weaker than expectations of +2.4% y/y.

German Feb retail sales unexpectedly fell -0.6% m/m, weaker than expectations of a +0.3% m/m increase.

ECB Governing Council member Madis Muller said, "The ECB can't rule out changes in interest rates already in April if energy prices remain at a high level for a long time."

Swaps are discounting a 50% chance of a +25 bp ECB rate hike at its next policy meeting on April 30.

US Stock Movers

The Magnificent Seven technology stocks are climbing today, helping lift the overall market.  Meta Platforms (META) is up more than +3%, and Amazon.com (AMZN), Microsoft (MSFT), Nvidia (NVDA), and Tesla (TSLA) are up more than +2%. Also, Alphabet (GOOGL) is up more than +1%, and Apple (AAPL) is up +0.81%.

Marvell Technology (MRVL) is up more than +7% to lead gainers in the Nasdaq 100, and chip stocks are higher after Nvidia said it is investing $2 billion in the company.  Also, ARM Holdings Plc (ARM) is up more than +4%, and Lam Research (LRCX) is up more than +3%. In addition, Western Digital (WDC), Seagate Technology Holdings Plc (STX), NXP Semiconductors NV (NXPI), KLA Corp (KLAC), Applied Materials (AMAT), ASML Holding NV (ASML), and Microchip Technology (MCHP) are up more than +2%.

Home builders and building suppliers are moving higher today after the 10-year T-note yield fell to a 1-week low, which lowers mortgage rates and supports housing demand. Builders Firstsource  (BLDR) and Lennar (LEN) are up more than +4%, and Toll Brothers (TOL) is up more than +2%.  Also, DR Horton (DHI), Pulte Group (PHM), and KB Home (KBH) are up more than +1%.

Apellis Pharmaceuticals (APLS) is up more than +136% after being acquired by Biogen for $5.6 billion, or about $41 a share.

Centessa Pharmaceuticals (CNTA) is up more than +45% after Eli Lilly agreed to buy the company for about $7.8 billion or $38 a share, plus a further $9 a share if three milestone targets are met.

Scholar Rock (SRRK) is up by more than +14% after it resubmitted its Biologics License Application for apitegromab, a muscle-targeted therapy for spinal muscular atrophy.

Nebius Group NV (NBIS) is up more than +7% after saying it plans to build a 310-megawatt server facility in Finland.

FactSet Research Systems (FDS) is up more than +4% after reporting Q2 revenue of $611 million, better than the consensus of $604.9 million, and raising its full-year revenue forecast to $2.45 billion to $2.47 billion from a previous estimate of $2.42 billion to $2.45 billion, above the consensus of $2.45 billion.

Phreesia (PHR) is down more than -23% after cutting its 2027 revenue forecast to $510 million to $520 million from a previous forecast of $545 million to $559 million, well below the consensus of $550.9 million.

McCormick & Co (MKC) is down more than -5% to lead losers in the S&P 500 after agreeing to acquire Unilever’s Food business for $15.7 billion in cash and $29.7 billion of stock.

Constellation Energy (CEG) is down more than -5% to lead losers in the Nasdaq 100 after forecasting 2026 adjusted operating EPS of $11 to $12.00, the midpoint below the consensus of $11.72.

Colgate-Palmolive (CL) is down more than -1% after TD Cowen downgraded the stock to hold from buy.

Earnings Reports(3/31/2026)

FactSet Research Systems Inc (FDS), McCormick & Co Inc/MD (MKC), nCino Inc (NCNO), NIKE Inc (NKE), PVH Corp (PVH), RH (RH), TD SYNNEX Corp (SNX). On the date of publication, Rich Asplund did not have (either directly or indirectly) positions in any of the securities mentioned in this article. All information and data in this article is solely for informational purposes. For more information please view the Barchart Disclosure Policy here.

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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

Haftungsausschluss: Der Text wurde mit Hilfe einer KI zusammengefasst und übersetzt. Für Aussagen aus dem Originaltext wird keine Haftung übernommen!

The S&P 500 Index ($SPX) (SPY) today is up +1.02%, the Dow Jones Industrial Average ($DOWI) (DIA) is up +0.67%, and the Nasdaq 100 Index ($IUXX) (QQQ) is up +1.10%.  June E-mini S&P futures (ESM26) are up +1.10%, and June E-mini Nasdaq futures (NQM26) are up +1.15%.

Stock indexes are moving sharply higher today after the Wall Street Journal reported that President Trump had signaled he was willing to end the US military campaign against Iran even if the Strait of Hormuz remains closed.  The report said Mr. Trump believes the US should wind down hostilities while pressuring Iran diplomatically to reopen the Strait.  If that fails, the US will press allies in Europe and the Gulf to take the lead on reopening the waterway.  US and Israeli forces pressed ahead with attacks on Iran today, while Iran hit a Kuwaiti oil tanker off Dubai in a drone attack, and the UAE reported a drone attack.

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Falling bond yields are also supportive of stocks, as the 10-year T-note yield dropped to a 1-week low of 4.30% today.  Bond yields are declining amid hopes that an end to the Iran war will lower energy prices, easing inflation concerns.  Stocks also found support today after the US Mar consumer confidence index unexpectedly rose.  Stock indexes fell back from their best levels as crude prices rose more than +1% to a 3-week high.

The US Jan S&P CaseShiller composite-20 home price index rose +1.18% y/y, weaker than expectations of +1.38% y/y and the smallest pace of increase in 2.5 years.

The US Mar MNI Chicago PMI fell -4.9 to 52.8, weaker than expectations of 55.0.

The Conference Board US Mar consumer confidence index unexpectedly rose +0.8 to 91.8, stronger than expectations of a decline to 87.9.

US Feb JOLTS job openings fell -358,000 to 6.882 million, weaker than expectations of 6.890 million.

Signs of strength in China’s economy are supportive for global growth prospects and stocks.  The China March manufacturing PMI rose +1.4 to 50.4, better than expectations of 50.1 and the strongest pace of expansion in a year.  Also, the China March non-manufacturing PMI rose by +0.6 to 50.1, better than expectations of 49.9.

Story Continues

Crude oil prices (CLK26) rose to a 3-week high today and remain supported despite President Trump signaling he is willing to end the war with Iran, as the Strait of Hormuz remains effectively closed.  The closure of the Strait of Hormuz, through which about a fifth of the world’s oil and natural gas flows, has choked off oil and gas flows due to Iran’s attacks on shipping in the waterway and forced Gulf producers to cut output because they can’t export from the region.  Iran is also seeking to control ship transit through the Strait of Hormuz, asking vessels to provide lists of crew and cargo, along with voyage details and bills of lading if they want to travel through the waterway.  Goldman Sachs warns that crude prices could exceed the 2008 record high of close to $150 a barrel if flows through the Strait of Hormuz remain depressed through March.

The International Energy Agency said last Monday that more than 40 energy sites across nine countries in the Middle East have been "severely or very severely" damaged, potentially prolonging disruptions to global supply chains once the war in Iran ends.

The markets are discounting a 3% chance for a +25 bp FOMC rate hike at the April 28-29 policy meeting.

Overseas stock markets are mixed today.  The Euro Stoxx 50 is up +0.83%.  China's Shanghai Composite fell from a 1-week high and closed down -0.80%.  Japan's Nikkei Stock 225 fell to a 3-month low and closed down -1.58%.

Interest Rates

June 10-year T-notes (ZNM6) today are up by +8 ticks.  The 10-year T-note yield is down -2.8 bp to 4.321%.  June T-notes rose to a 1-week high today, and the 10-year T-note yield fell to a 1-week low of 4.295%.  T-notes are climbing today on hopes that an end to the Iran war will lower energy prices and ease inflation concerns.  T-notes fell from their best level after the US Mar consumer confidence index unexpectedly rose.

European government bond yields are moving lower today.  The 10-year German bund yield is down -0.6 bp to 3.029%.  The 10-year UK gilt yield is down -2.0 bp to 4.914%.

Eurozone Mar CPI rose +2.5% y/y, the most in 14 months, but below expectations of +2.6% y/y.  Mar core CPI rose +2.3% y/y, weaker than expectations of +2.4% y/y.

German Feb retail sales unexpectedly fell -0.6% m/m, weaker than expectations of a +0.3% m/m increase.

ECB Governing Council member Madis Muller said, "The ECB can't rule out changes in interest rates already in April if energy prices remain at a high level for a long time."

Swaps are discounting a 50% chance of a +25 bp ECB rate hike at its next policy meeting on April 30.

US Stock Movers

The Magnificent Seven technology stocks are climbing today, helping lift the overall market.  Nvidia (NVDA) and Meta Platforms (META) are up more than +3%, and Amazon.com (AMZN), Tesla (TSLA), and Alphabet (GOOGL) are up more than +2%.  In addition, Microsoft (MSFT) is up more than +1%, and Apple (AAPL) is up +0.48%.

Marvell Technology (MRVL) is up more than +8% to lead gainers in the Nasdaq 100, and chip stocks are higher after Nvidia said it is investing $2 billion in the company.  Also, ARM Holdings Plc (ARM) is up more than +6%, and Western Digital (WDC), ON Semiconductor (ON), and Sandisk (SNDK) are up more than +5%.  In addition, Seagate Technology Holdings Plc (STX) is up more than +4%, and Lam Research (LRCX), Broadcom (AVGO), Intel (INTC), and Microchip Technology (MCHP) are up more than +3%.  Finally, NXP Semiconductors NV (NXPI), KLA Corp (KLAC), Applied Materials (AMAT), and ASML Holding NV (ASML) are up more than +2%.

Home builders and building suppliers are moving higher today after the 10-year T-note yield fell to a 1-week low, which lowers mortgage rates and supports housing demand. Builders Firstsource (BLDR) and Toll Brothers (TOL) are up more than +2%.  Also, Lennar (LEN) and Pulte Group (PHM) are up more than +1%, and KB Home (KBH) is up more +0.42%, and DR Horton (DHI) is up +0.40%.

Apellis Pharmaceuticals (APLS) is up more than +136% after being acquired by Biogen for $5.6 billion, or about $41 a share.  Biogen (BIIB) is down more than -4% on the news.

Centessa Pharmaceuticals (CNTA) is up more than +44% after Eli Lilly agreed to buy the company for about $7.8 billion or $38 a share, plus a further $9 a share if three milestone targets are met.

Scholar Rock (SRRK) is up by more than +12% after it resubmitted its Biologics License Application for apitegromab, a muscle-targeted therapy for spinal muscular atrophy.

FactSet Research Systems (FDS) is up more than +7% to lead gainers in the S&P 500 after reporting Q2 revenue of $611 million, better than the consensus of $604.9 million, and raising its full-year revenue forecast to $2.45 billion to $2.47 billion from a previous estimate of $2.42 billion to $2.45 billion, above the consensus of $2.45 billion.

Nebius Group NV (NBIS) is up more than +5% after saying it plans to build a 310-megawatt server facility in Finland.

Phreesia (PHR) is down more than -26% after cutting its 2027 revenue forecast to $510 million to $520 million from a previous forecast of $545 million to $559 million, well below the consensus of $550.9 million.

Constellation Energy (CEG) is down more than -8% to lead losers in the S&P 500 and Nasdaq 100 after forecasting 2026 adjusted operating EPS of $11 to $12.00, the midpoint below the consensus of $11.72.

McCormick & Co (MKC) is down more than -6% after agreeing to acquire Unilever’s Food business for $15.7 billion in cash and $29.7 billion of stock.

Colgate-Palmolive (CL) is down more than -2% after TD Cowen downgraded the stock to hold from buy.

Earnings Reports(3/31/2026)

FactSet Research Systems Inc (FDS), McCormick & Co Inc/MD (MKC), nCino Inc (NCNO), NIKE Inc (NKE), PVH Corp (PVH), RH (RH), TD SYNNEX Corp (SNX).

On the date of publication, Rich Asplund did not have (either directly or indirectly) positions in any of the securities mentioned in this article. All information and data in this article is solely for informational purposes. This article was originally published on Barchart.com

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